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The Humanicsxian: November 09: Issue 06
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The Humanicsxian: November 09: Issue 06
















|| Editorial || Israel: Palestine: World Humanity: Stop Fighting and Killing: Stop Following Pseudo-Reasoning: No Power Had Ever Been Able to Enforce Peace Since the Dawn of Time Because Peace Is the Outcome of Righteousness of Reason: Stop the Slaughter NOW and Strive For Peace For Blessed Are the Peace-Makers ||

|| Friday: October 27: 2023 || ά. Imagine, dear Reader, that this Universe, the Mother Universana, is the Mammothcrosm of the seismic dot of this Mother Earth, who is the nanocrosm of that Mammothcrosm, with whom the miniscule super-nano-dot, the Moon, is attached and she is The Mother of Existence and Life on this Temporal Universe, that appears and disappears at the same time eternally. She is no Christian, no Jew, no Muslim, no Buddhist, no Jain, no Rasta, no Deist, no Atheist. No adjective ought to be added before her mighty name for she has already got the highest, infinite name: The Mother. And we begin this Editorial with the Mother of the Editor-In-Chief of this Publication, of this Mother Universana, had told him this story when he was learning to stand and walk, learn and grow: This is the story his great Philosopher of a Mother told him once:  

Once upon a time, there was a Young Man. He was one of the poorest of the poor of the rich Kingdom of the Glorious, where the most beautiful, most intelligent and most rich Princess Humana lived in high honour in high riches, whom the whole Kingdom’s young men loved and sought to woe. Among them was this Poor Young Man. Suppose he had name, Mad. So, like every other young men of the Kingdom, Mad was in love with Humana and, unlike the any other of his competitors, he was absolutely mad about her and he lived and died in each of his breath for The Princess.

|| Astrophysics || NASA’s Bennu Asteroid Sample Contains Carbon and Water: And Water Contains the Duo-Jewels of Life: Oxygen and Hydrogen: Already A School of Life ||

|| Sunday: October 15: 2023 || ά. Initial studies of the 04.5-billion-year-old asteroid Bennu sample, collected in space and brought to Earth by NASA show evidence of high-carbon content and water, which together could indicate the building blocks of life on Earth may be found in the rock. NASA made the news Wednesday from its Johnson Space Centre in Houston where leadership and scientists showed off the asteroid material for the first time since it landed in September. 

This finding was part of a preliminary assessment of NASA’s Origins, Spectral Interpretation, Resource Identification and Security: Regolith Explorer: OSIRIS-Rex, science team. “The OSIRIS-REx sample is the biggest carbon-rich asteroid sample ever delivered to Earth and will help scientists investigate the origins of life on our own planet for generations to come.” Said NASA Administrator Bill Nelson. “Almost, everything we do at NASA, seeks to answer questions about who we are and where we come from.

|| Ecology || The First Evidence That Albatrosses Use Infrasound to Navigate Long Journeys ||

|| Saturday: October 14: 2023 || ά. A new Study by the University of Liverpool provides the first evidence that wandering albatrosses, one of the widest-ranging seabirds, may use infrasound to help them navigate long and featureless foraging trips covering thousands of miles. In a Paper, published in the journal Proceedings of the National Academy of Sciences, researchers from the University’s School of Environmental Sciences show that albatrosses orientate towards areas of ‘loud’ microbarom infrasound when flying on long distance foraging trips. 

Infrasound is a form of low-frequency sound, inaudible to humans but is ubiquitous in the marine environment.  Microbaroms are a type of infrasound, associated with colliding ocean waves. Such wavy areas are, also, associated with strong winds, which albatrosses depend on to help them fly efficiently. The researchers used GPS trackers to determine the flight paths of 89 wandering albatrosses breeding in the Crozet Islands archipelago, Southern Ocean, over the course of their foraging trips to sea, which can last up to a month.

|| Immunology || Streptococcus Pyogenes Molecule Illuminates Cancer Immune Therapies ||

|| Tuesday: October 10: 2023 || ά. Researchers at Harvard Medical School have discovered that a molecule, made by Streptococcus pyogenes, the bacterium, that causes strep throat and other infections, could help explain several long-standing medical mysteries: Why strep sometimes leads to serious immune complications, including rheumatic fever. How the immune system's recognition of the molecule may contribute to diseases like lupus.

Or why one of the first cancer immunotherapies showed promise more than 100 years ago. How current immune therapies for cancer could be more effective. The findings contradict a long-standing belief that the immune system ignores this bacterial molecule and could propel efforts to tame or activate the immune system to treat a range of diseases. The research team, led by the lab of HMS biochemist Jon Clardy, published its findings in the Journal of the American Chemical Society.

|| Bacteriology || Scientists Identify Gut Bacteria Linked to Bone Density and Bone Strength ||

|| Tuesday: October 10: 2023 || ά. Evidence is mounting that the microbes, residing in the human gut, play a role in a range of physiologic functions, including immunity, metabolism, inflammation and, even, mental health. A new Study, led by Harvard Medical School researchers at Hebrew Senior Life, links the gut microbiome to, yet another, important aspect of human health: bone density and strength.

The research, published in Frontiers of Endocrinology, identified tantalising links between certain bacteria and critical dimensions of bone health. “We found patterns in which greater abundance of microbiota were associated with worse measures of bone density and micro-architecture.” Said the Principal Investigator Professor Douglas Kiel, HMS professor of medicine and Senior Scientist at the Marcus Institute for Aging Research at Hebrew Senior Life.

|| Biomedicoengineering || The Total-Body Positron Emission Tomography Scanner Will Enable Scotland Unlock Better Images of Diseases ||

|| Sunday: October 08: 2023 || ά. Scotland is set to receive its first total-body scanner in a boost to clinical research, that aims to improve the detection, diagnosis and treatment of complex, multi-organ diseases. The Total-Body Positron Emission Tomography:PET facility, due to be operational in 2024, will capture whole-body images of patients in more detail and use less radiation than existing scanners.

In combination with data from the other new scanner in London, the Scotland scanner forms part of a new National PET Imaging Platform:NPIP, which, experts believe, will accelerate the development of new drugs and diagnostics. The platform, a partnership between Medicines Discovery Catapult:MDC, the Medical Research Council:MRC and Innovate UK, aims to advance healthcare research and clinical trials and unlock new treatments for complex diseases like cancer, as well as, cardiovascular and neurological diseases.

|| Molecular Biology || Professor Naomi Hamburg Awarded $03.7 Million to Study How Endothelial Cell Health Impacts Disease ||

|| Sunday: October 08: 2023 || ά. Professor Naomi Hamburg, MD, the Joseph A Vita Professor of Medicine at Boston University Chobanian and Avedisian School of Medicine, has been awarded $03.7 million grant from the National Heart, Lung and Blood Institute for her research study, ‘Endothelial Cell Health Across the Spectrum of Cardiometabolic Disease’. Cardiometabolic diseases are a group of common but, often, preventable conditions, including heart attack, stroke, diabetes, insulin resistance and non-alcoholic fatty liver disease.  

The escalating prevalence of cardiometabolic risk factors, including obesity and type two diabetes mellitus:T2DM, presents a critical cardiovascular challenge. Individuals with cardiometabolic disease harbour greater risk of cardiovascular disease:CVD, including accelerated vascular aging and premature blood vessel blockages. Importantly, changes in the endothelial cells, that line blood vessels predate the development of clinical CVD. Endothelial cell health is a window into early heart disease risk. Getting a glimpse into endothelial cells from people has potential to help create new treatments to protect blood vessel health. “Experimental studies and our prior work link altered metabolism to organelle, sub-cellular structure, that has one or more specific jobs to perform in the cell stress, including mitochondrial dysfunction and stress.

|| Psychiatry || New Study: Black Women 18–65 Have the Highest Suicide Risk Among Women ||

|| Sunday: October 08: 2023 || ά. Suicide is the second leading cause of death in America among individuals, 10-34 and the fourth leading cause of death for individuals, 35-44. Suicide attempts, non-fatal, self-directed potentially injurious behaviour with any intent to die, and self-inflicted injuries represent a major risk factor for completed suicides. In 2020, more than 01.2 million people over the age of 18 reported a suicide attempt in the country. 

And hundreds of thousands more presented to hospitals with self-harm injuries. Although, there is data on gender disparity in suicide:self-inflicted injury rates few studies have examined the factors, associated with suicide:self-inflicted injury in females. In a new Study, looking only at women, researchers from Boston University Chobanian and Avedisian School of Medicine and Howard University have identified Black women, 18–65, to have the highest risk for suicide irrespective of their socio-economic status.

|| Epidemiology || The First Epidemiological Study Links Popular Weight-loss Drugs to Stomach Paralysis and Other Serious Gastro-intestinal Conditions ||

|| Friday: October 06: 2023 || ά. First epidemiological study links popular weight-loss drugs to stomach paralysis, other serious gastro-intestinal conditions. They’re being hailed as an effective way to lose weight but diabetes drugs like Ozempic may come with a heightened risk of severe gastro-intestinal problems.

That’s according to new research from the University of British Columbia showing that medications, known as GLP-1 agonists, which includes brands like Wegovy, Ozempic, Rybelsus and Saxenda, are associated with an increased risk of serious medical conditions, including stomach paralysis, pancreatitis and bowel obstruction.

|| Medicine || New Immunotherapy Treatment For Leukaemia Possible ||

|| Thursday: October 05: 2023 || ά. Researchers have identified a novel immunotherapy for acute myeloid leukaemia:AML. Immune cells are programmed to recognise a mutation, found in leukaemia patients. The results provide hope for new and effective treatment for the most common form of leukaemia in adults. Blood cells are formed and matured in the bone marrow.

However, sometimes mutations or damage occur in the cells' genetic material. This can lead to uncontrolled growth of blood cells and improper maturation. AML is a type of acute blood cancer where the bone marrow gets overcrowded with such immature blood cells. "AML is a disease with a very poor prognosis. With standard treatment, one-third of patients have a five-year survival rate after diagnosis." Says Professor Johanna Olweus, who is a professor at the University of Oslo and the Head of Department of Cancer Immunology at the Cancer Clinic at Oslo University Hospital and a world-leading researcher in immunotherapy.








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|| Mother Earth || The Ozone Hole Goes Large Again ||

|| Thursday: October 05: 2023 || ά. Measurements, from the Copernicus Sentinel-5P satellite, show that this year’s ozone hole over Antarctica is one of the biggest on record. The hole, which is what scientists call an ‘ozone depleting area,’ reached a size of 26 million square kilometre on September 16, 2023. This is roughly three times the size of Brazil. The size of the ozone hole fluctuates on a regular basis. From August to October, the ozone hole increases in size, reaching a maximum between middle of September and middle of October.

When temperatures high up in the stratosphere start to rise in the southern hemisphere, the ozone depletion slows, the polar vortex weakens and finally breaks down and by the end of December ozone levels return to normal. Launched in October 2017, Copernicus Sentinel-5P, short for Sentinel-5 Precursor, is the first Copernicus satellite dedicated to monitoring our atmosphere. It is part of the fleet of Copernicus Sentinel missions, that ESA develops for the European Union’s environmental monitoring programme.

|| United Kingdom || NHS Trusts Are Earning Hundreds of Millions of Pounds in Private Income: New Study Shows Their Clear Direction Towards Commercialisation ||

|| Tuesday: October 03: 2023 || ά. Hospital trusts are relying more and more on private income to boost their finances, with one Trust making more than half their income from commercial activities, a new Study has shown. NHS organisations are implementing strategies to make income from commercial activities.

University of York academics looked at six high-profile NHS trusts as case studies and found them to be making between 12% and 53% of their total income from commercial activities in 2021:22, including activity from treating private patients and running labs and pharmacies to establishing branches abroad.

|| Epidemiology || Malaria Kills Nearly Half a Million Children in the African Region Every Year: The World Health Organisation Recommends R21:Matrix-M Vaccine For Malaria Prevention ||

|| Monday: October 02: 2023 || ά. The World Health Organisation:WHO has recommended a new vaccine, R21:Matrix-M, for the prevention of malaria in children. The recommendation follows advice from the WHO: Strategic Advisory Group of Experts on Immunisation:SAGE and the Malaria Policy Advisory Group:MPAG and was endorsed by the WHO Director-General, following its regular bi-annual meeting, held on September 25-29.

The R21 and RTS.S vaccines act against P. falciparum, the deadliest malaria parasite and the most prevalent on the African continent. The updated WHO recommendation for malaria vaccines was informed by the results of the WHO-co-ordinated Malaria Vaccine Implementation Programme, through which nearly two million children in Ghana, Kenya and Malawi have been reached with the RTS.S:AS01 malaria vaccine since 2019.